The JAK2V617F mutation can occur in a hematopoietic stem cell that exhibits no proliferative advantage: a case of human allogeneic transplantation.

نویسندگان

  • Kristien Van Pelt
  • Friedel Nollet
  • Dominik Selleslag
  • Laurent Knoops
  • Stefan N Constantinescu
  • Arnold Criel
  • Johan Billiet
چکیده

1. Ang SO, Chen H, Hirota K, et al. Disruption of oxygen homeostasis underlies congenital Chuvash polycythemia. Nat Genet. 2002;32:614-621. 2. Percy MJ, Zhao Q, Flores A, et al. A family with erythrocytosis establishes a role for prolyl hydroxylase domain protein 2 in oxygen homeostasis. Proc Natl Acad Sci U S A. 2006;103:654-659. 3. Percy MJ, Furlow PW, Lucas GS, et al. A gain-of-function mutation in the HIF2A gene in familial erythrocytosis. N Engl J Med. 2008;358:162-168. 4. Howarth C, Chanarin I, Janowska-Wieczorek A, et al. Familial erythrocytosis. Scand J Haematol. 1979;23:217-222. 5. Warnecke C, Zaborowska Z, Kurreck J, et al. Differentiating the functional role of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha (EPAS-1) by the use of RNA interference: erythropoietin is a HIF-2alpha target gene in Hep3B and Kelly cells. FASEB J. 2004;18:1462-1464.

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عنوان ژورنال:
  • Blood

دوره 112 3  شماره 

صفحات  -

تاریخ انتشار 2008